ACQUITY M-Class HDX System
Integration of Hydrogen-Deuterium Exchange (HDX) Method with High-Resolution MS
Many harmful immune responses and diseases are believed to be caused by changes in protein conformation. Until now, X-ray crystallography and NMR-based analyses have primarily been used to measure protein conformation. While these analytical methods are useful, they are not applicable to all proteins and often require high-purity, large quantities of samples. Today, by effectively combining the ACQUITY M-Class HDX system with high-resolution mass spectrometry and rigorously controlling the temperature-sensitive aspects of the HDX sample preparation, we can reliably identify changes in protein conformation. This has made it possible to obtain detailed information about protein conformation. The ACQUITY M-Class HDX system adds a new dimension of separation capability, reproducibility, and durability to chromatography. 【Features】 - Binding of drugs to target molecules of proteins - Development of biopharmaceuticals - Protein-protein interactions - Research in structural biology For more details, please contact us or download the catalog.
- Company：日本ウォーターズ（米国本社 Waters Corporation）
- Price：Other
